1 of 20Lisa Edelstein and Hugh Laurie, House
We are fans of simmering sexual tension, so when Cuddy (Edelstein) and House (Laurie) decided to finally have a go at it in last season's finale, we were skeptical. Interestingly though, their relationship is more familiar than the typical TV coupling. While Cuddy weighs how to tell their colleagues, House struggles with surrogate fatherhood when he has to baby-sit Cuddy's daughter Rachel. Their chemistry is still white-hot, but their interactions have the stuff of longevity.
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