In this episode of Grey's Anatomy, Derek works through the jitters as he returns to the OR for the first time since he lost his last patient, and Cristina continues to deal with Owen's post-traumatic stress disorder when it takes a seriously dark turn. Plus, Karev learns the importance of sticking by your loved ones while the other residents deal with Izzie's sickness in their own ways. So did Izzie come out of her first (of many) surgeries OK? Let's find out!
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