- Father was Powhatan Indian and Irish; mother was Cherokee Indian and German.
- Originally performed as part of duet with his older brother Jerry.
- Discovered by Jackie Gleason at a Phoenix luncheon; Gleason put the brothers on TV in 1962, and Newton appeared on Gleason's variety show several more times.
- Nicknamed "Mr. Las Vegas" for appearing in thousands of shows in Sin City casinos.
- Las Vegas' McCarran International Airport's main thoroughfare is named "Wayne Newton Boulevard."
- Signed one of the biggest contracts in entertainment history in 1999 with the Stardust Resort and Casino.
- Received the Lifetime Achievement award from the Arabian Horse Breeders Alliance in 2007.
- Signature song is "Danke Schoen."
- Evelyn Newton — Mother
- Elaine Okamura — Ex-wife
- Erin Newton — Daughter
- Kathleen McCrone — Wife
- Lauren Ashley Newton — Daughter
- Patrick Newton — Father
- Jerry Newton — Brother
- Marla Heasley — Ex-fiancée