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Capt. Holt and Jake contract the mumps during an investigation and become quarantined together in hopes of solving the case. Meanwhile, Rosa tries to help Boyle through a mourning process; and Terry is forced to clean up Hitchcock and Scully's mess.
Charles and Genevieve want to take their relationship to the next level, but his ex-wife, Eleanor, intervenes; and Amy asks Terry to write a letter of recommendation. Meanwhile, Holt and Rosa enlist Gina's help to solve a case.
Jake and Amy go on a cruise together, but their vacation is spoiled when they discover an old adversary is on board with them. Meanwhile, Gina and Terry help Capt. Holt survive a visit from his sister; and Charles and Rosa vie for the same apartment.