- Moved from Michigan to New York City to pursue a career in fashion photography, before becoming more interested in acting.
- Studied acting at New York's Stella Adler Conservatory and the Column Theater.
- Appeared as a monkey and a baby in surreal theatre productions at the Little Theatre of the Green Goose in Kalamazoo, MI.
- Made her TV debut in a 1995 episode of Nickelodeon cult favorite The Adventures of Pete & Pete.
- Had a breakout year in 1999, starring in big-screen teen drama Cruel Intentions and on the WB sitcom Zoe, Duncan, Jack & Jane.
- A spokesperson for the Get REAL for Kids campaign.
- Is an avid equestrian.
- Matthew Felker — Ex-significant Other
- Catherine — Sister
- Marie Cooke — Sister
- Molly Cooke — Mother
- Lizzie Lies — Sister
- Arthur Saint Bleick — Son
- Ahmet Zappa — Ex-husband
- Jason Schwartzman — Ex-significant Other
- Jason Bleick — Ex-significant Other
- Mikey Day — Ex-significant Other
- Elliot Beitner — Father
- University of Michigan, Ann Arbor, MI (BA and BFA in English and Fine Arts, 1995); attended New York University, New York, NY; attended Kalamazoo College, Kalamazoo, MI
- Birth Name: Selma Blair Beitner
- Birth Place: Southfield, MI
- Birthday: June 23, 1972, Cancer
- Profession: Actor
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Grey's Anatomy is obviously a big influence on Tay Tay