- Played basketball in high school in addition to swimming.
- Earned gold (4x200 freestyle relay) and silver (200m individual medley) medals at the 2004 Olympic Games in Athens.
- Broke SEC records that were 11 years old (100m butterfly) and nine years old (400m IM) while attending the University of Florida.
- Won his first individual gold medal at an international long-course event in the 200m backstroke at the 2007 World Championships, snapping Aaron Peirsol's seven-year win streak in the event. The next month, Lochte also broke Peirsol's six-year unbeaten streak in the 100m backstroke.
- Posed in a fashion shoot for VMan magazine and a "Got milk?" print ad along with other Olympians and graced the August 2008 cover of Men's Journal with Michael Phelps.
- Ike Lochte — Mother
- Devon Lochte — Brother
- Brandon Lochte — Brother
- Kristin — Sister
- Steve Lochte — Father
- Megan — Sister
- University of Florida, Gainesville, FL (BS in Sports Management, 2006)