Zach persuades Claire to go to the homecoming dance.
Claire warns her step-mother about her headaches.
Hiro finally finds love in his life, and his powers interfere.
Gabriel meets Chandra and is eager to take part in Chandra's research on evolution.
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Dee takes a job as a substitute drama teacher and shows her students the gang's take on the Lethal Weapon series: Lethal Weapon 5.
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In the climactic season finale, everyone bands together in an effort to stop Samuel (Robert Knepper) from taking the lives of thousands. Peter (Milo Ventimiglia) joins forces with his most unexpected ally to save Emma (guest star Deanne Bray). Meanwhile, H.R.G.?s (Jack Coleman) life hangs in the balance as he and Claire (Hayden Panettiere) find themselves trapped underground with oxygen quickly running out. Elsewhere, Hiro (Masi Oka) starts to come to grips with the decisions he has made and is called into action to help stop a disaster. Greg Grunberg, Ali Larter, Zachary Quinto and James Kyson Lee also star. David H. Lawrence XVII, Harry Perry, Todd Stashwick also guest star.
In the season finale, the heroes race to thwart Samuel's vengeful plan to kill thousands of innocent people in Central Park. Volume Six: Brave New World begins.
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Peter finds himself trapped in Sylar's nightmare as Samuel forges ahead with his despicable plan.
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