A teenage military trainee at a juvenile offender training camp suffers peculiar symptoms after enduring an intense training course, and mysteriously, his drill sergeant is soon admitted for similar symptoms. Unable to track down the cause of the shared illness, the team searches for clues in the trainee?s family medical history, and Masters (guest star Tamblyn) and House reveal a unique bond between the sergeant and trainee. Meanwhile, when an indecent photo of Chase is posted on a social-networking site following three different romantic encounters, Chase is determined to find out which girl is trying to publicly disgrace him. Also, sensing Cuddy?s stress over her daughter Rachel?s enrollment at a prestigious preschool, House secretly prepares Rachel for observations and reveals a soft spot for the toddler.
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Samuel (Robert Knepper) prepares for new additions to his family, while Lydia (guest star Dawn Olivieri) warns him of the consequences. Claire (Hayden Panettiere) discovers that her roommate Gretchen (guest star Madeline Zima) may have a hidden agenda. Meanwhile, Peter (Milo Ventimiglia) finds an unexpected way to connect with Emma (guest star Deanne Bray), who would prefer to stay distant. Elsewhere, a different side of Sylar (Zachary Quinto) emerges as he desperately tries to remember the person he used to be. Masi Oka and Cristine Rose also star. Rachel Melvin and Jack Wallace also guest star.
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Claire (Hayden Panettiere) struggles with adjusting to her new life in college when a mysterious death thrusts her into the spotlight once again. Elsewhere, Hiro (Masi Oka) and Ando (James Kyson Lee) continue their noble quest to help people by promoting their abilities. Angela (Cristine Rose) fears Nathan (Adrian Pasdar) will soon discover his true identity; while Matt (Greg Grunberg) is haunted by an unexpected visitor seeking something he has lost. Tracy Strauss (Ali Larter) and H.R.G. (Jack Coleman) join forces, looking for the key to unlock the motive behind a horrific crime. Meanwhile, Peter (Milo Ventimiglia) uses his abilities for good, but he is soon called upon to aid an old friend. While the heroes adjust to their new surroundings, a mysterious carnival clan, led by ringleader Samuel (Robert Knepper), sets their sights on familiar faces. James Kyson Lee and Zachary Quinto also star. Rachel Melvin, Jimmy Jean-Louis, Ashley Crow, Lisa Lackey, Assaf Cohen, and Saemi Nakamura also guest star.
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