Hugh Laurie
House, a risky, challenging and altogether different kind of medical drama, premiered on November 16, 2004, and turned the genre on its head with a true antihero lead: a doctor who has overt disdain for his patients — and people in general. But thanks to compelling writing and a career-defining performance by British improv-comedy vet Hugh Laurie, the show stayed on the air for eight seasons of abuse (both drug and verbal) and countless diagnoses that were almost never lupus. As House prepares to sign off for good (Monday, May 21 at 8/7c on Fox), TVGuide.com talked to the show's creators and cast about building the Emmy-winning drama from the ground up. This is the first of a two-part series....
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