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Part 1. Matt tries to help a vengeful drifter whose friends were trampled by a rancher's horsemen. Parker: John Ireland. Johnson: James Stacy. Matt: James Arness. Festus: Ken Curtis. Zack: Morgan Woodward. Angel: Kim Darby. Newly: Buck Taylor.
Matt enforces a quarantine on a railroad car while Doc treats the passengers for a fever that could spread. Isabel: Dana Wynter. Doc: Milburn Stone. Matt: James Arness. Townsend: Morgan Woodward. Loftus: Norman Alden. Bright: Ed Bakey.