- Won the Boston College Male Scholar Athlete Award in 2004.
- Named the 2007 Johnny Unitas Golden Arm Award winner.
- Selected by the Atlanta Falcons with the third pick in the 2008 NFL draft and went on to win the 2008 NFL Offensive Rookie of the Year.
- His first pass in the NFL was a 62-yard touchdown to Michael Jenkins.
- Played high-school football with former NBA guard Sean Singletary.
- Nickname is "Matty Ice".
- Bernice Ryan — Mother
- Michael Ryan — Father
- John Loughery — Uncle
- Sarah Marshall — Fiancée
- Boston College, Boston, MA
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