- Has a fraternal twin sister, Ruth.
- Was a classmate of Ugly Betty's Michael Urie at Juilliard, where MacFarlane attended on a four-year drama scholarship.
- Big break was as Private Frank "Dim" Dumphy in the short-lived FX series Over There (2005).
- Made his film debut in 2004's Kinsey, as the son of sex researcher Alfred Kinsey (played by Liam Neeson).
- Emboldened by the positive response toward his gay character on Brothers & Sisters, he disclosed his homosexuality in April 2008.
- Rebecca — Sister
- Ruth MacFarlane — Sister
- Thomas MacFarlane — Father
- Penny MacFarlane — Mother
- The Juilliard School, New York, New York, United States (2003)
Season 2, Episode 17
- Birth Name: Thomas Luke MacFarlane Jr.
- Birth Place: London, Ontario, Canada
- Birthday: January 19, 1980, Capricorn
- Profession: Actor
- User Rating:
- Your Rating: