Jodi Lyn O'Keefe

TVGuide.com: Had you seen The Big Bang Theory before?
Jodi Lyn O'Keefe: Oh yes. I'm [series creator] Chuck Lorre's biggest fan, and have been working with him my whole life. He usually brings me on to the shows that he's doing to either guest-star or recur. I couldn't be happier. 

TVGuide.com: Right, you've been on Two and a Half Men...
O'Keefe: Twice, and I recurred on Dharma & Greg.... I adore Chuck — he is one of the funniest men in Hollywood. He really knows how to write. 

TVGuide.com: Let's talk about Big Bang Theory's Mikayla.
O'Keefe: I'm a hooker ... read more 8 Comments

What happens in Vegas ... apparently will be played for maximum comic effect when the boys of The Big Bang Theory cross paths with Prison Break alumna Jodi Lyn O'Keefe.

In the CBS hitcom's April 27 episode, Leonard and Koothrappali escort a heartbroken Wolowitz to Las Vegas. There, O'Keefe boots the geeks' hard drives as Mikayla, a "working girl" — and not in the Melanie Griffith vein.

Meanwhile... read more 4 Comments

Has Gretchen committed her last double cross? For now, yes. Jodi Lyn O'Keefe's season-and-a-half Prison Break run came to a close this week when the former Company operative took a bullet in the belly and got carted away by EMTs, never to be seen again — this season, at least. TVGuide.com spoke with O'Keefe about her admirably extended stint on the Fox series where, like 24, nobody is ever truly safe.

TVGuide.com: You made it pretty far; 28 episodes is pretty impressive on this show.
Jodi Lyn O'Keefe: To be a bad guy, yeah. 

TVGuide.com: And to be a female.
O'Keefe: That's also true. I'll give myself extra credit for that! 

TVGuide.com: Are you happy that they kept Gretchen alive? Do you think it was for a reason?
O'Keefe: Yeah, I do. At the beginning of the year it was touch-and-go. There even was an article about how ... read more 14 Comments

Can't these assorted archenemies just get along? "I think the Company is asking for trouble," Jodi Lyn O'Keefe (Gretchen) tells TVGuide.com. "Putting these people together ... read more 9 Comments