Taught himself to play piano, organ and saxophone.
Joined Stax Records as a backup pianist in 1964, where his first session was with Otis Redding.
Cowrote (with David Porter) such all-time classics as "Soul Man" and "When Something Is Wrong With My Baby."
Laid the groundwork for both disco and rap with such classic LPs as Hot Buttered Soul (1969), The Isaac Hayes Movement (1970) and Shaft (1971).
Nicknamed "Black Moses."
Inducted into the Rock and Roll Hall of Fame in 2002.
Gave voice to South Park's Chef until 2006, when he quit after an episode criticized Scientology.
Involved in humanitarian efforts in the West African country of Ghana; his commitment was honored by King Nene Kubi III, who bestowed a kingship on Hayes in 1992. at his coronation, Hayes was given the royal moniker Nene KateyOcansey I.
1972, Golden Globe — Best Original Song - Motion Picture: Nominee
1972, Golden Globe — Best Original Score - Motion Picture: Winner
2005, Screen Actors Guild Awards — Outstanding Performance by a Cast in a Motion Picture: Nominee
1972, BAFTA Film Awards — The Anthony Asquith Award: Nominee
1971, Oscar — Best Achievement in Music (Original Dramatic Score): Nominee
1971, Grammy — Best Original Score Written For A Motion Picture Or A Television Special: Winner
1971, Oscar — Best Achievement in Music (Song--Original for the Picture): Winner
1971, Grammy — Best Instrumental Arrangement: Winner
1972, Grammy — Best Pop Instrumental Performance by an Arranger, Composer, Orchestra and/or Choral Leader: Winner