- At the age of 16, won the Junior Mr. Victoria bodybuilding competition.
- Landed a role on the long-running Australian soap Neighbours soon after graduating from Geelong College.
- Was nominated for Most Promising Actor at the Chicago Film Critics Awards for his American movie debut, the 1997 crime drama L.A. Confidential.
- Won Best Actor at the Las Vegas Film Critics Awards and the San Diego Film Critics Awards for the acclaimed 2001 thriller Memento.
- Returned to the stage after a seven-year absence as the star of Poor Boy, a 2009 Australian play based on the music of fellow Aussie Tim Finn.
- Spoke at the 2011 dedication ceremony for Colin Firth's star on the Hollywood Walk of Fame.
- Declined the lead in the 2003 adaptation of Daredevil as he didn't want to play a comic-book superhero, but the role of villainous Aldrich Killian changed his mind and he appeared in Ironman 3 in 2013.
- 2012, Golden Globe — Best Performance by an Actor in a Supporting Role in a Series, Miniseries or Motion Picture Made for Television: Nominee
- 2014, AACTA Awards — Best Lead Actor: Nominee
- 2012, AACTA Awards — Best Lead Actor: Nominee
- 2010, Australian Film Institute Awards — Best Supporting Actor: Nominee
- 2011, Screen Actors Guild Awards — Outstanding Performance by a Male Actor in a Television Movie or Miniseries: Nominee
- 2005, Australian Film Institute Awards — Best Lead Actor: Nominee
- 2009, Australian Film Institute Awards — International Award for Best Actor: Nominee
- 1997, Screen Actors Guild Awards — Outstanding Performance by a Cast in a Motion Picture: Nominee
- 2010, Screen Actors Guild Awards — Outstanding Performance by a Cast in a Motion Picture: Winner
- 2008, Australian Film Institute Awards — Best Lead Actor: Nominee
- 2011, Emmy — Outstanding Supporting Actor in a Miniseries or a Movie: Winner
- Carice van Houten — Significant Other
- Anne Pearce — Mother
- Tracey Pearce — Sister
- Kate Mestitz Pearce — Wife (separated)
- Laurie Cocking — Stepfather
- Stuart Pearce — Father
- Monte Pearce — Son
- Birth Name: Guy Edward Pearce
- Birth Place: Ely, Cambridgeshire, England
- Profession: Actor
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