- Attended a private Quaker boarding school.
- As a child, he began his entertainment career as a magician and musician.
- An accomplished banjo player, he performed in the band Bruno Lynch and His Imperial Jazz Band during his college days.
- Served in the Army for several years.
- As an aspiring actor, he toiled as a janitor at Circle in the Square Theatre in New York.
- Pulled out of the lead role in Blake Edwards' popular 1979 film 10.
- Played the banjo in the Beverly Hills Unlisted Jazz Band, which played a gig at Carnegie Hall in 1981, opening for Steve Lawrence and Eydie Gorme.
- In 1996, staged a career comeback playing Mary Tyler Moore's husband in the romantic comedy Flirting with Disaster, which led to a lead role on NBC's sitcom Just Shoot Me from 1997 to 2003.
- 1966, Oscar — Best Performance by an Actor in a Supporting Role: Nominee
- 1967, Golden Globe — Best Performance by an Actor in a Supporting Role in a Motion Picture: Nominee
- 1974, Golden Globe — Best Performance by an Actor in a Motion Picture - Musical or Comedy: Winner
- 1999, Golden Globe — Best Performance by an Actor in a Television Series - Musical or Comedy: Nominee
- 1969, BAFTA Film Awards — Best Supporting Actor: Nominee
- 2000, Golden Globe — Best Performance by an Actor in a Television Series - Musical or Comedy: Nominee
- 1965, Golden Globe — New Star of the Year - Actor: Winner
- Sonia Schultz — Wife
- George Segal Sr. — Father
- Marion Sobel — Ex-wife
- Linda Rogoff — Wife (deceased)
- Elizabeth Segal — Daughter
- Polly Segal — Daughter
- Fannie Segal — Mother
- Attended Haverford College, Haverford, Pennsylvania, United States; Columbia University, New York, New York, United States
- Birth Place: Great Neck, New York, United States
- Profession: Actor, Musician
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