- Made his MLB debut on Sept. 2, 1997 as a pinch hitter for the Minnesota Twins.
- Finished his first season with the Boston Red Sox (2003) with 31 home runs, 101 RBIs and a .288 batting average.
- Was named to his first All-Star team in 2004 while helping lead Boston to its first World Series title since 1918.
- In 2006, set the Red Sox single-season record for home runs with 54.
- Won the Home Run Derby at the 2010 All-Star Game, his sixth.
- Received the 2011 Roberto Clemente Award, an honor given annually to an MLB player for sportsmanship and community involvement.
- Claimed World Series MVP honors in 2013 in winning his third championship with Boston.
- Supports pediatric critical care in the Dominican Republic and the Northeast U.S. through his David Ortiz Children's Fund.
- Angela Rosa Arias — Mother
- Tiffany Brick — Wife
- Jessica Ortiz — Daughter
- D'Angelo Ortiz — Son
- Alexandra Ortiz — Daughter