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A witch sacrifices people in a small town to summon a demon who may be a key to freeing Satan. To stop her, Castiel brings in a special angel who intends to destroy the town.
Sam and Dean search for a young woman who can hear conversations between angels after Ruby tells them a powerful demon is on the prowl to find her.
A seductive siren compels three men to murder their wives in a small Iowa town. Sam and Dean investigate and fall under her spell, leading them to engage in a battle against one another.
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