- Was class president in high school.
- Studied at the Stella Adler Studio of Acting in New York City.
- Along with comedy partner June Diane Raphael, whom she met at New York University, cocreated the two-woman sketch-comedy show Rode Hard and Put Away Wet.
- Named one of the "10 Comics to Watch" by Variety in 2008.
- Was a featured player on Saturday Night Live during the 2008-09 season.
- Cowrote, with Raphael, the screenplay for the 2009 comedy Bride Wars; they both also had supporting roles.
- Has contributed to the humor Web site Funny or Die.
- First starring TV role came with the ABC sitcom Happy Endings.
- Fletcher Todd Wilson — Brother
- Paul O. Wilson — Father
- Marion 'Red' Higdon — Grandfather
- David Caspe — Husband
- Kathleen Anne Higdon Wilson — Mother
- New York University, Tisch School of the Arts, New York, New York, United States