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An ailing Princeton-Plainsboro pathologist doesn't trust any of his colleagues to diagnose and treat him, except for House—who's missing. So House's team must make the skeptical patient believe that House is actually directing his case.
A murder victim made himself few friends by being overly honest, and team members find out why when they begin being more honest with each other. Meanwhile, Angela urges Hodgins to deal with the fact that she's pregnant.