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Sam visits a town where ordinary people are turning into violent murderers. His investigation reveals that the Men of Letters came to the town in 1958. Meanwhile, Dean struggles with effects from the Mark of Cain and is tested by Crowley.
Abaddon demands that Crowley help her kill Sam and Dean. When he refuses, she reveals a shocking bargaining chip to change his mind. Meanwhile, Castiel captures one of Metatron's angels, and gets Sam and Dean to help him with the interrogation.
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