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Mickey O'Connor

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Bill Lawrence on the New Scrubs: "Give It a Chance"

Dave Franco, Michael Mosley, Nicky Whelan, Kerry Bishé

Executive producer Bill Lawrence says that the Scrubs we all knew and loved is over. Sure, Zach Braff & Co. will be sticking around for a few episodes to help launch the new Scrubs, but Lawrence thinks the new cast is just as funny and endearing as the old one. TVGuide.com spoke to Lawrence about how he decided to reboot the series, who will be checking in to the show's medical school and what fans of the old show can expect of the new.

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Coolest Moments: A Biggest Loser Surprise, a Glee Kiss, and a Monk Goodbye

Glee, Monk

This week TV did its best to impress us. Top Chef and Melrose Place shocked us with left-field developments. Monk's departure was both conclusive and heartfelt. SNL put its cast's prodigious comedy talents on display. And The Biggest Loser proved that changing one's body can change one's life. Welcome to Top Moments: Dressed to Impress Edition.

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The Brand Manager: Dick Wolf's Family of Crime Dramas Took Advance Planning

Dick Wolf

Former advertising executive Dick Wolf got his start in television writing for shows like Hill Street Blues and Miami Vice. But his greatest accomplishment is Law & Order, which mastered the TV-show-as-brand concept by cornering the market on cops-and-courts procedurals. (This year it ties Gunsmoke's record for longest-running scripted television program.) L&O laid the groundwork for two successor series: Law & Order: SVU and Law & Order: Criminal Intent. Wolf, one of the influential television industry players interviewed for TVGuide.com's Best of the Decade section, talked with us about the germ of the idea that led to his gritty TV empire. He also told us what he watches.

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The Bookworms: Lost's Damon Lindelof and Carlton Cuse Have Made Cerebral Appointment TV

Carlton Cuse, Damon Lindelof

Lost is one of the most influential shows on television, but also one of the most influenced. Executive producers Damon Lindelof and Carlton Cuse (or "Darlton," as they're known to fans) have created a baffling, intensely seductive story that blends sci-fi, fantasy, mystery, romance, and more than a little comedy. You can probably guess both men are obsessive consumers of pop culture, from Star Wars to The Prisoner. But they're also well-read writers whose obsessions stretch from ancient mythology to Stephen King. Fans obsess over whether the show is rooted in Greek myth, the Old Testament, both, or something else entirely. We spoke to Lindelof and Cuse, who are among the influential television industry players interviewed for TVGuide.com's Best of the Decade section, about who inspired them, why they set an end date for the show, and how they created their own myths.

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The Polymath: J.J. Abrams Does Everything on His Shows, and Does Everything Well

J.J. Abrams

J.J. Abrams is a former actor (he was hilarious in Six Degrees of Separation) who also happens to direct, produce, write, and dream. We can't be too sorry he's focusing on his work behind the camera. If he hadn't, we might never have been formally introduced to Alias' Sydney Bristow, Fringe's Dr. Walter Bishop or any of Lost's fascinating ensemble of enigmas. We spoke to Abrams, who is one of the influential television industry players interviewed for TVGuide.com's Best of the Decade section, about the impact his shows have made, why he creates so many strong female characters and who inspired him.

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The Humanist: Shonda Rhimes Hones In on Ethical, Moral Grey Areas

Shonda Rhimes

Shonda Rhimes wants her characters to feel like human beings — even if it makes them less likable. Rhimes revels in her characters' moral and ethical gray areas. In the first episode of Grey's Anatomy, the title character (Ellen Pompeo) goes binge-drinking before enjoying a one-night stand with a strange man. It didn't necessarily make her lovable, but it made her feel real. We spoke to Rhimes, who is among the influential television industry players interviewed for TVGuide.com's Best of the Decade section, about how The West Wing and Buffy inspired her, her race-blind approach to casting and what she's learned about portraying lesbians on television.

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Desperate Housewives: Wisteria Lane Kid Spills Secrets

Beau Mirchoff, Desperate Housewives

Desperate Housewives troubled teen Danny Bolen (the polite Canadian actor Beau Mirchoff) has seen better days. At the end of the Nov. 29 episode, Danny was hospitalized after taking a fistful of pills. He's OK, but he's insisting that the nurse call him Tyler, which is presumably his given name, from before his family went on the run. TVGuide.com spoke to Mirchoff about how Danny is involved in Sunday's plane-crash story line, who he'll befriend and/or romance and how long the Bolens will be sticking around.

TVGuide.com: How did things go so wrong for Danny?
Mirchoff: He's been on the run his whole life, he's never really had a solid friendship or long-lasting relationship... read more

Coolest Moments: Surprises from Glee, Meredith Baxter, FlashForward and More!

Glee, FlashForward

This week, television surprised and moved us. Meredith Baxter announced that she is gay. Sons of Anarchy shifted its focus abruptly from revenge to deep sorrow. And House admitted that without Wilson, he is truly alone. Also: Nathan Petrelli is dead and the ladies of Eastwick are witches. (OK, so not everything was a surprise.) Welcome to the Coolest Moments (aka Top Moments): Shock and Awwww Edition.

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Ugly Betty Moving to Wednesdays

Ugly Betty

Ugly Betty is moving to Wednesdays, TVGuide.com has confirmed.

The show will replace... read more

Nigel Barker's Generation Free: AIDS Prevention in Africa

Nigel Barker

Photographer and filmmaker Nigel Barker — best known for sitting on Tyra Banks' judging panel on America's Next Top Model — also donates his time to the Elizabeth Glaser Pediatric AIDS Foundation. Most recently, Barker directed Generation Free, a 45-minute documentary that chronicles the Foundation's efforts to create a generation of children free of the HIV virus in Tanzania. In commemoration of World AIDS Day, Generation Free will air on the TV Guide Network on Tuesday, Dec. 1 at 7/6c (the film repeats at 10/9c, or you can watch it in its entirety here).

TVGuide.com spoke to Barker about why his film focuses on Tanzania, what is being done to prevent mother-to-child transmission of the virus and how working in Africa has inspired his activism.

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