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Charlie Sheen, Two and a Half Men
Sheen was on the receiving end of a pink slip in March 2011 after he had a very public meltdown and trashed series creator Chuck Lorre to any and all media outlets. Because of his exploits and subsequent firing, Men was put on hiatus early and lost an estimated $10 million in expected revenue from the unmade episodes. Sheen, who was replaced by Ashton Kutcher, attempted a make-good at the Emmys that fall, saying, "From the bottom of my heart, I wish you nothing but the best for this upcoming season. We spent eight wonderful years together and I know you will continue to make great television."