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Up All Night (NBC)
Despite its initial winning formula and a host of comedic talent (Christina Applegate, Will Arnett, Maya Rudolph and executive producer Lorne Michaels) in front of and behind the camera, the sitcom died a slow, painful death in its second season. After losing creator Emily Spivey, there was talk of rebooting it as a multi-camera comedy. Soon , Applegate left and, after a revolving door of showrunners, NBC finally put it out of its misery. Which is probably a good thing: We liked the show the way it was.