Chelsea Handler, David Letterman

Chelsea Handler appeared on The Late Show Friday night and — no surprise — the comedienne didn't hold back.

As the two stars discussed the craziness of the recent late-night headlines, David Letterman mentioned he's lucky to have any job, even if it was mowing lawns. But Handler apparently doesn't think Letterman is suited for physical labor: "Well yeah, you're a small man," she said.

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Handler quickly apologized, but when the host brought up the comment later, she defended herself. "You're not particularly large though. You're very dainty for a man. You have to be honest," she said, adding, "And I mean that in the nicest way possible. Yes. I mean, you're fit."

"You're kind of hefty for a broad. I didn't mean that the way it sounded," Letterman joked back.

Watch the full burn below.