Jon Cryer, Courtney Thorne- Smith

Two and a Half Men's longest-running couple, Alan (Jon ­Cryer) and former porn star Lyndsey (Courtney Thorne-Smith), will call it quits on the April 25 episode of the CBS comedy.

"They've broken up so many times, but this one feels more real," Thorne-Smith says. "There's no one thing for her; it just isn't working."

But the actress isn't yet looking for her next gig: "They have said I will be around in some capacity," she says. "Who knows? It could be cleaning up or working the craft service table."

Subscribe to TV Guide Magazine now!