George Clooney

George Clooney, Gwyneth Paltrow, Will Smith, Denzel Washington and Renee Zellweger are among the list of celebrities who will appear on the fundraising TV special Stand Up to Cancer.

The special, airing Sept. 10 at 8/7c, will be preceded by an online pre-show hosted by Cat Deeley.

Stand Up to Cancer special aligns its stars

Other additions to the lineup include: Elizabeth Banks, Kathy Bates, Emily Deschanel, Bill Hader, Dorothy Hamill, Anne Heche, Cheryl Hines, Rob Lowe, Marlee Matlin and Olivia Munn.

Musical guests include Billie Joe Armstrong of Green Day, Neil Diamond, The Edge, Herbie Hancock, Kris Kristofferson, Lady Antebellum and Leona Lewis.

Stand Up to Cancer will be simulcast commercial-free on ABC, CBS, FOX, NBC, Bio, Current TV, Discovery Health, E!, G4, HBO, HBO Latino, MLB Network, mun2, Showtime, Smithsonian Channel, The Style Network, TV One and VH1. Network news anchors Katie Couric, Diane Sawyer and Brian Williams will host the event. The broadcast will air in 195 countries, as well as on the Armed Forces Network. 

Fox, Jake Gyllenhaal join Stand Up to Cancer cause

SU2C co-founder Laura Ziskin, the broadcast's executive producer and a cancer survivor herself, urged viewers in a statement "to see your favorite stars, who'll ask, 'Will you stand up with us?' Person by person, saying 'yes' moves us toward a goal completely within our grasp: a world without cancer. A donation of any size brings scientists one step closer to a cure."

Deeley of Fox's So You Think You Can Dance will host the pre-show promotion to kick off the evening as the celebrity phone bank opens a half-hour before airtime. Also online, and following the show: a 30-minute jam session featuring musical guests Fitz and the Tantrums, Orianthi, Natasha Bedingfield and Heart