Caterina Scorsone

The Shepherd siblings will be repairing their relationship in the upcoming season of Grey's Anatomy.

Caterina Scorsone, who's been upped to series regular on Private Practice, will appear in the third episode of Grey's Season 7, executive producer Shonda Rhimes tells TVGuide.com.

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Scorsone's Dr. Amelia Shepherd goes to Seattle to reconcile with her brother, Derek (Patrick Dempsey). The two have not been on speaking terms since Amelia turned to drugs while grieving the death of her father, who was shot and killed in front of her and Derek.

"Family is family," Scorsone tells TVGuide.com. "Regardless of the strife and tension and drama between the family members, there's a bond and a connection that is so deep. Obviously Amelia has a lot of emotion surrounding Derek and that relationship and all the things they've been through together. There's a lot of unresolved emotions surrounding that whole relationship."

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Amelia will be reluctant to head to Seattle to see her brother, though she'll get a supportive push from Addison (Kate Walsh) to reconcile. "Everyone can relate to that fear of confronting situations that may result in rejection," says Scorsone.

Grey's Anatomy returns Thursday, Sept. 23 at 9/8c.