My Boys alum Jordana Spiro has landed the lead in Fox's untitled drama from Drop Dead Diva's Josh Berman and Robert Wright, and Justified's Michael Dinner.
Spiro will play Grace Delvin, a thoracic surgeon who splits her time between her career and her lifelong debt to the South Chicago mob.
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Jamie Lee Kirchner (Necessary Roughness) has also been cast to play a surgical resident who is the daughter of the hospital's chairman. James Carpinello and Jesse Lee Soffer are set to co-star.
Aside from her role on My Boys, Spiro has recently appeared on Harry's Law and Dexter.