Paul Reiser

Paul Reiser is returning to television with The Paul Reiser Show, NBC announced Tuesday.

The single-camera comedy will star Reiser as himself debating his next career move after years of being off the air. His hit series Mad About You ended in 1999.

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Rounding out the cast: Amy Landecker (A Serious Man) as his wife, Claire, and Ben Shenkman (Angels in America), Omid Djalili (The Infidel), Duane Martin (All of Us) and Andrew Daly (MADtv) as his unlikely group of friends.

The Paul Reiser Show will debut Thursday, April 14 at 8:30/7:30c, replacing Perfect Couples.