Oprah Winfrey

The final episode of The Oprah Winfrey Show is set to air May 25, TVGuide.com has confirmed.

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In November 2009, Oprah Winfrey announced she would end the long-running syndicated talk show after 25 years. Though Oprah has been in repeats recently, Winfrey tweeted Thursday that she was "hard at work planning the final shows."

Winfrey currently runs OWN network, which launched on Jan. 1.