Calista Flockhart, Carmine Giovinazzo and Dana Delany

Every week, editors Mickey O'Connor and Adam Bryant answer your burning questions. Want some TV scoop? Please send all questions to mega_scoop@tvguide.com.

How serious is Kitty's illness on Brothers & Sisters? Nora looked really upset in the promos. — Bev
ADAM: Nora has plenty of reason to sob: Kitty's ailment is of the life-threatening variety. But before anyone can focus on her grim prognosis, Kitty will have to break the news to Robert, who is in the midst of his own health-related crisis.

I can't wait to see how Katherine gets her revenge on Susan on Desperate Housewives. — Kelly
MICKEY: I'm with you, Kelly! The thought of a brooding, bilious Dana Delany makes my cold, black heart sing as well, but my mole tells me that Susan will not takes things lying down. Just as she did at her wedding, Susan will confront Katherine at every turn, which will be problematic when the gun she's holding accidentally goes off.

Please don't say CSI: NY's Danny will be paralyzed for good! He can't be sitting in a wheelchair. He is so much better at getting the bad guys and being out in the field. — Judy
ADAM: Fine, Judy, I won't, and neither will executive producer Pam Veasey. She promises we'll see Danny back on his feet, but it won't be overnight... or easy. And for anyone worried about the health of his relationship with Lindsay, know this: It's only through her encouragement that Danny will find the strength to make it through physical therapy.

Fringe is making me crazy! How am I supposed to know which universe we're in? — Craigger
MICKEY: "Have we been secretively 'over there' when there weren't clues?" asks executive producer Jeff Pinkner. "No. When Olivia crosses over, she will be aware and the audience will be aware. We're not trying to trick anybody." Easy for you to say, Jeff! If you're still confused about what happened to Olivia in that "car crash," fear not: I have it on very good authority that an upcoming episode will deal with that issue head-on, so to speak.

Do you have any Mark/Lexie scoop for Season 6 of Grey's Anatomy? Love them! — L.E.
ADAM: I know you won't believe me when I say this, but they're going to have problems. "They've got some obstacles for sure, but some of our more emotional moments have come from them," executive producer Krista Vernoff tells me. That doesn't mean the coupling won't survive, however. "We've done a lot of stories about people coming together, and now we have an opportunity to tell stories about people who are together," Vernoff says.

How soon before we discover the identity of Willi's mystery visitor on Ugly Betty? — Jamie
MICKEY: You won't have to wait very long at all actually, but you may not recognize him or her after the big reveal. In this case, though, it's not the who that's important, it's the why, and it marks the beginning of a storyline that spotlights Willi's special talent for deception.

What direction will the Foster/Lightman relationship take this year on Lie to Me? — Kate
ADAM: Executive producer Shawn Ryan will promise only movement on the relationship front. "It's something we're going to take a little slowly, but it's something we also take seriously," he says. "You'll see the nature and the intimacy of their relationship, even if it doesn't end up landing them in bed together." But could Lightman take a possible detour to Zoetown? "There's always the possibility that those two could wind up in the back of a car in some parking lot at any moment," Ryan teases.

Are Navid and Adrianna really going to break up on 90210? I love them together! — Katelyn
MICKEY: Well, that's hard to say. I wonder if it has to do with Teddy? I hope it doesn't send Ade back to substance abuse.

I can't wait to see Hilary Duff on Gossip Girl. Who will she have scenes with? — Andrea S.
MICKEY:
Who won't she have scenes with? I had heard that movie star Olivia Burke (Duff) would be rooming with Vanessa, but I had no idea she'd be romancing Dan and working with Serena. (Yes, you heard me right: working.) But forget all that, if you're looking for an excuse to laugh louder than you ever have in your life honest human emotion, wait until you see Duff and fellow guest star Tyra Banks' virtuoso performances in Fleur, the film-within-the-show about, of course, the French resistance. Talk about Les Miserables!

Since we know Violet survives the premiere of Private Practice, please tell me they won't just drop that storyline and act like everything is OK. — Megan
ADAM:
"It's still present," Kate Walsh says. "That's one thing that's so great about [creator Shonda Rhimes]. She doesn't just resolve something quickly and move on, she kind of plays [with] the reality of the situation. You're going to see a big shift in Violet and everybody in the practice about the aftermath of it. It doesn't just go away in one episode." Happy?

Clark and Chloe deserve to be friends at least. The season premiere tore their friendship apart and I don't want to watch Smallville anymore. — Josh
ADAM: Wrongs can always be undone, Josh. Sure, Chloe and Clark have a long way to go in repairing their friendship, but by the end of the next episode, I think you will be hopeful about them patching things up. The bad news for Chlark fans is this: Chloe's friendly gesture pushes Clark closer to Lois.

Any scoop on Modern Family's Mitchell and Cameron? — Tully
MICKEY: "They'll be walking the tightrope of being new dads and wanting to do everything perfectly," says Jesse Tyler Ferguson, who reports that Cameron and Mitchell will sign up for a Mommy and Me class and try their damnedest to blend in. Unfortunately, this will end with them in the pediatrician's office, where Lily's well-being will be backburnered while Cam and Mitch make sure they appear sufficiently culturally sensitive to the baby's Asian doctor.

Adam's Mega Rave: I didn't really watch Lie to Me last season, but after Monday's premiere, I'm definitely adding it to my rotation. Shield creator Shawn Ryan added a nice punch of adrenaline, evidenced by Tim Roth's extreme interrogation of a patient with multiple personalities (a fantastic Erika Christensen) that would make Vic Mackey proud.

Mickey's Mini Rant: I don't watch reality shows; I mostly read and listen to NPR. But Nicolas' win on Project Runway for his jackass ice-queen "costume" was the worst thing that has ever happened in the universe.

Reader Quote of the Week: "If they reset time so that they are on the plane and it doesn't crash, does that mean that Walt will suddenly shrink back to his Season 1 size?" — zaza, on what the bomb exploding will mean for Lost's sixth season.

Crave scoop on your favorite TV shows? E-mail Mickey and Adam at mega_scoop@tvguide.com or drop us a line at Twitter.com/TVGuide. The question you don't ask is a question we can't answer!

(Additional reporting by Natalie Abrams)