Keck's Exclusives: Up All Night Casts Nurse Jackie Fave and Gay Neighbors

Eve Best

Complications are coming up for Christina Applegate's Reagan Brinkley both at work and home on NBC's Up All Night. Actress Eve Best, who steals every scene she's in as Nurse Jackie's Dr. Eleanor O'Hara, has landed a role equivalent to Alec Baldwin's bossy character on 30 Rock. Eve will play a corporate mogul named Yvonne Encanto who takes ownership of The Ava Show, where Reagan works.

Yvonne also just happens to be Reagan's idol. As her first order of business, Yvonne instates her lieutenant, Luke (Rescue Me's Steven Pasquale) as the show's day-to-day, hands-on boss, whose hands might just end up on Ava (Maya Rudolph).

And on the home front, Reagan and husband Chris (Will Arnett) are about to get some gay neighbors. Playing the part of the Brinkley's new best friends are actors Nat Faxton (co-writer of The Descendants and a voice actor on The Cleveland Show and Allen Gregory) and Ben Falcone (husband of Mike & Molly's Melissa McCarthy). All will go swimmingly with the new besties until a certain deal-breaker rocks the boat.

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