Katherine Heigl, Grey's Anatomy

In Thursday night's episode, Izzie returns to Grey's Anatomy after the three-episode hiatus that Katherine Heigl took to shoot a film. Don't get used to her being around, however. Heigl will be taking another leave of absence, TVGuide.com has confirmed.

Katherine Heigl and Husband adopting a girl

Heigl, 30, is going on a belated maternity leave to spend some time with Naleigh, the daughter she and husband Josh Kelley adopted.

Katherine Heigl debuts photos of new baby

Reps for the ABC series declined to comment on when and how Dr. Izzie Stevens will take off again. Entertainment Weekly, which first reported the story, said she'll likely be missing in action until early 2010.