Jesse Spencer

Jesse Spencer is wasting no time plotting his post-House career.

Spencer, who has been on the Fox medical drama for the last eight seasons, will star in Dick Wolf's Chicago Fire pilot at NBC, Deadline reports.

Lisa Edelstein will not return for House series finale

Spencer, 33, will play Matthew Casey, a natural leader at Firehouse 55 who is struggling in his personal life after recently separating from his wife. Taylor Kinney is also starring in the pilot.

Spencer's casting follows that of House co-star Peter Jacobson, who signed on for a possible recurring role on Showtime's Ray Donovan pilot shortly after Fox announced that House would wrap in May.