Robert Sean Leonard, House

Lost alum Cynthia Watros is checking into House, TVGuide.com has confirmed.

Watros, 41, will play James Wilson's (Robert Sean Leonard) first ex-wife and the doctor's rekindled love interest, according to a show insider. She is set to appear in multiple episodes.

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The Emmy winner (for Guiding Light) is best known as Libby on Lost, a role she is set to reprise this season. Since being killed off the show in 2006, she's guest-starred on Men of a Certain Age and starred in a string of failed pilots, including last year's Gossip Girl spin-off Valley Girls

Do you think Watros and Leonard will make a good match?