"Cuddy has a complicated relationship with men, it seems," says Edelstein. "She likes the screwed-up ones!"

Coming up this week on Fox's House (Mondays, 8 pm/ET), at least one sect of 'shippers will have their wildest dream come true when Dr. Crankpot and Cuddy (presumably) leave their animus on the nightstand in the name of getting horizontal.

"It's a pretty hot scene," Lisa Edelstein, who plays Cuddy, tells TVGuide.com. When we asked the actress if the characters' coupling was "good" and thus worth the long (long) wait, she answered: "Uh, apparently!"

Edelstein also shared during a Friday press conference call that the sex (or is it love?) scene took at least five takes, because "the cameras wanted to capture a lot of different things." But that was fine by her and longtime pal Hugh Laurie.

"I have a great friendship with Hugh," she said, "and he's super-sexy — so who could complain about kissing him?"

But to paraphrase Sam the piano player: Is a romp just a romp? Will Cuddy and House's physical encounter lay the groundwork for emotional intimacy as well?

"I don't think it's a passing thing. It's been going on a long time, whether or not they've acted on it," said Edelstein. But... "I don't necessarily think it will be a satisfying relationship in terms of both of them settling in and saying, 'This is what you're doing.'"

Then again, the increasingly hallucinatory Dr. House could — could — just be imagining the whole she-bang. Allows Edelstein, "There's a chance for anything, isn't there?"

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