TVGuide.com's 2010 Golden Globes Predictions

Dexter, Julie and Julia
You told us some of your Golden Globes picks, and now it's time for us to share ours. Behold: Our choices for this year's top races. Agree? Disagree? Sound off below!
The Golden Globes ceremony, hosted by Ricky Gervais, airs live Sunday, Jan. 17 at 8/7c on NBC.
Check out the full list of Golden Globe nominees
Watch Live at the Golden Globes Red Carpet with Carrie Ann Inaba and Chris Harrison, Sunday, Jan. 17, at 6 ET/3 PT on TV Guide Network, and watch live fashion cam video of all the red carpet arrivals on TVGuide.com starting at 6 ET/3 PT.
TELEVISION
Drama Series
Will win: Mad Men
Fun fact: No drama series has ever three-peated at the Globes before (The X-Files came the closest with three wins in four years, interrupted by Party of Five), but if any show can set a trend, it's Mad Men.
Watch out for: Dexter
For a killer season.
Comedy/Musical Series
Will win: Modern Family
The critically acclaimed sitcom pairs wacky and witty into one perfect, uh, family, and we all know the Hollywood Foreign Press Association loves new blood.
Watch out for: Glee
It leads all TV nominees with four nominations and is the breakout hit of the season.
Drama Actor
Will win: Michael C. Hall, Dexter
Always the bridesmaid and never the bride, Hall might finally get his hands on a trophy for a buzzed-about season that ended right when nominations were announced. Talk about perfect timing.
Watch out for: Jon Hamm, Mad Men
Hamm delivered his best work yet in Season 3.
Drama Actress
Will win: Julianna Margulies, The Good Wife
Margulies, who's never won a Globe, is compelling as the take-charge Alicia Florrick in a well-received new drama.
Watch out for: January Jones, Mad Men
For Betty's confrontation with Don alone. Here's hoping that abysmal Saturday Night Live hosting gig won't be held against her.
Comedy/Musical Actor
Will win: Alec Baldwin, 30 Rock
He's already a two-time champ, but who could beat the comically cruel Jack Donaghy?
Watch out for: Matthew Morrison, Glee
Morrison carries the show and puts the "musical" in the category name.
Comedy/Musical Actress
Will win: Courteney Cox, Cougar Town
Snubbed throughout Friends' 10-year run, Cox may finally get overdue recognition thanks to her charming over-the-top sitcom comeback.
Watch out for: Edie Falco, Nurse Jackie
The two-time Globe champ followed up Carmela Soprano with a multifaceted role that is far more dark and droll than Toni Collette's multiple personalities in United States of Tara.
Supporting Actor in a Series, Miniseries or TV Movie
Will win: John Lithgow, Dexter
The always bold and brilliant Lithgow made Trinity so much more than just your average serial killer.
Watch out for: Neil Patrick Harris, How I Met Your Mother
Someone has to start rewarding him.
Supporting Actress in a Series, Miniseries or TV Movie
Will win: Jane Lynch, Glee
Sue Sylvester. 'Nuff said.
Watch out for: Janet McTeer, Into the Storm
The TV movie/miniseries nominees always have an edge.
FILM
Drama Picture
Will win: Up in the Air
At this point, it's a tight race between four films with only Precious being the longshot, but Up in the Air, which perfectly captures the economic zeitgeist, should eke out the win.
Watch out for: Avatar
Never count out the epic blockbuster.
Comedy/Musical Picture
Will win: (500) Days of Summer
Fresh and enchanting, the non-linear anti-romance could charm its way into voters' hearts. Plus, Nine bombed, The Hangover is too bawdy for the old folk; and Meryl Streep (It's Complicated, Julie & Julia) may split her films' votes.
Watch out for: It's Complicated
If they must pick Meryl, they'll go for this one.
Drama Actor
Will win: George Clooney, Up in the Air
Clooney's A-list pedigree could lift him to the podium over the equally worthy and virtuoso performances of Jeff Bridges (Crazy Heart) and Colin Firth (A Single Man). On top of that, we kind of want to see Doug Ross and Carol Hathaway win on the same night.
Watch out for: Jeff Bridges, Crazy Heart
A career best for a veteran performer.
Drama Actress
Will win: Carey Mulligan, An Education
The Globes love ingénues in breakthrough roles.
Watch out for: Sandra Bullock, The Blind Side
For a phenomenal year.
Comedy/Musical Actor
Will win: Joseph Gordon-Levitt, (500) Days of Summer
Two months ago, Daniel Day-Lewis looked to be the favorite, but with Nine tanking, this may be the night's most open-ended race. A hilarious Matt Damon (The Informant!) may split votes (he's also nominated in supporting actor for Invictus), paving the way for Gordon-Levitt to snag his first Globe. Besides, JGL's musical number trumps DDL's.
Watch out for: Michael Stuhlbarg, A Serious Man
A strong performance in a little-seen film.
Comedy/Musical Actress
Will win: Meryl Streep, Julie & Julia
She's up against herself for It's Complicated, but Streep should snare lucky Globe No. 7 for her transformative turn as the late Julia Child to become the winningest Globe champ ever.
Watch out for: Marion Cotillard, Nine
A heartwrenching turn in a rather lackluster film.
Supporting Actor
Will win: Christoph Waltz, Inglourious Basterds
No contest. Nothing tops Waltz's glorious bastard of a villain.
Watch out for: Woody Harrelson, The Messenger
He steals the show in the film and is generating the late-season buzz.
Supporting Actress
Will win: Mo'Nique, Precious
Done deal. Her tour de force performance may be as unrivaled as Heath Ledger's mercurial Joker last year.
Watch out for: Anna Kendrick, Up in the Air
See Mulligan.