Katie Couric

Katie Couric signed off as the anchor of CBS Evening News on Thursday, calling the last five years an "incredible journey."

It was business as usual for most of Couric's last night behind the desk, which kicked off with a piece from her Evening News successor Scott Pelley. The broadcast also included a rare interview with Secretary of State and former First Lady Hillary Clinton.

Scott Pelley to replace Katie Couric on CBS Evening News

However, Couric called her attention to her final broadcast in the last five minutes, saying it was an "extraordinary privilege to sit in this chair" and a "real honor" to work at CBS. She then introduced a package looking back at the "history-making" events and people of the last five years.

The package included her interviews with Presidents George W. Bush and Barack Obama, Vice President Joe Biden, Michael J. Fox, Alex Rodriquez, ousted CIA agent Valerie Plame and her famous 2009 sit-down with then-Vice Presidential candidate Sarah Palin. The look back also included world events such as the War on Terror, the Virginia Tech shooting, Obama's inauguration, the BP oil disaster, the death of Osama bin Laden and the recent Royal Wedding.

Katie Couric to replace General Hospital?

"To all of you watching, thank you so much for coming along with me on this incredible journey," Couric concluded.

Pelley will take over CBS Evening News beginning June 6. Couric, the first solo female anchor of a nightly news broadcast, has yet to announce her next move. She is widely expected to move to ABC to launch a syndicated daytime talk show in fall 2012.