Michael Weston, Sela Ward

CSI: NY has booked former House and Six Feet Under actor Michael Weston to play Frank, a former FBI crime lab agent who worked with Jo (Sela Ward) in Washington, TVGuide.com has learned exclusively.

But the duo's reunion likely won't be a happy one.

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They formerly worked together on a case involving the rape of a U.S. senator's daughter — Jo's last case before leaving the FBI for New York. Because of Frank's mistake in processing evidence — and Jo's refusal to hide the mistake — serial rapist John Curtis (Jason Wiles) was released. When Curtis strikes again in New York, Frank comes to visit Jo. Anyone else think he might hold a grudge?

Curtis' new case will also bring Sen. Matthews (Jeffrey Nordling) and daughter Serena (Jenn Proske) to New York in hopes that Curtis will finally get the punishment they feel he deserves.

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Weston's episode is slated to air Nov. 18. He's perhaps best known for his role as Dr. Gregory House's preferred private investigator, Lucas Douglas. He also played homicidal meth addict Jake on Six Feet Under and has appeared on such shows as Scrubs, ER and Burn Notice.

CSI: NY airs Fridays at 9/8c on CBS.