After having brain surgery in the Season 4 finale, Booth's personality has changed drastically, as we'll see vividly in the show's season premiere (Thursday, 8/7c, Fox).

How will that affect Bones and Booth's relationship? Series stars Emily Deschanel and David Boreanaz both sat down with TVGuide.com to discuss Booth's recovery. Will love blossom as he convalesces? Boreanaz has a different question: "What if they never do get together?"

Find out what else is in store this season...