Betty White and Sandra Bullock

Betty White is "deeply, deeply saddened" for The Proposal castmate Sandra Bullock amid reports of her husband's infidelity.

"At such a high point in her life, it's tough," White told Entertainment Tonight, "but I think the less other people have to say about it and let her work it out, it is [for] the better."

Jesse James apologizes to Sandra Bullock: "I deserve everything bad coming my way"

Jesse James, Bullock's husband of five years, publicly apologized to his wife and his children for his "poor judgment" Thursday and asked for their forgiveness. A day earlier, In Touch printed a cover story featuring an interview in which model Michelle "Bombshell" McGee claimed to have carried on an 11-month affair with James while Bullock was filming The Blind Side.

Bullock has since pulled out of the London and German premieres for The Blind Side. The 45-year-old actress won the Oscar earlier this month for her performance in the football drama.

Blind Side's German premiere canceled due to Bullock's absence

"I love her with all my heart," White, 88, told ET. "[She's] one of the greatest human beings on the planet."

White will next co-host Saturday Night Live on May 8 alongside series alums such as Tina Fey and Amy Poehler. She is also scheduled to appear on the season finale of The Middle.